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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1808158생성일: 2026년 10월 25일

3-Fluoro-4-(trifluoromethyl)benzylamine → 4-{[(5-Chloro-1,3-thiazol-2-yl)amino]sulfonyl}-2-cyano-N-[3-fluoro-4-(trifluoromethyl)benzyl]benzamide

https://huagongshe.com/reaction/1808158

반응식

참여 물질

역할이름HCID투입량
반응물3-Fluoro-4-(trifluoromethyl)benzylamineHCID 2737567—
반응물4-{[(5-Chloro-1,3-thiazol-2-yl)amino]sulfonyl}-2-cyanobenzoic acidHCID 86630781—
생성물4-{[(5-Chloro-1,3-thiazol-2-yl)amino]sulfonyl}-2-cyano-N-[3-fluoro-4-(trifluoromethyl)benzyl]benzamideHCID 57732196—

반응 단계

The title compound was prepared from 3-fluoro-4-(trifluoromethyl)benzylamine and 4-{[(5-chloro-1,3-thiazol-2-yl)amino]sulfonyl}-2-cyanobenzoic acid of Preparation 22, following Method O described for Example 344. The reaction mixture was stirred at room temperature for 18 hours.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08357711B2
출처 데이터셋uspto-grants-2013_01
ORD IDord-0421cfd3fdb94f7581d5516e348cb354
출처 메모uspto-grants-2013_01