tert-Butyl (2S)-2-(aminomethyl)piperidine-1-carboxylate → (S)-2-[(6,7-Difluoro-3-methylquinoxaline-2-ylamino)methyl]-piperidine-1-carboxylic acid tert butylester
반응식
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][CH2:10][C@H:9]1[CH2:14][NH2:15])=[O:7])([CH3:4])([CH3:3])[CH3:2].Cl[C:17]1[C:26]([CH3:27])=[N:25][C:24]2[C:19](=[CH:20][C:21]([F:29])=[C:22]([F:28])[CH:23]=2)[N:18]=1>CN(C=O)C>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][CH2:10][C@H:9]1[CH2:14][NH:15][C:17]1[C:26]([CH3:27])=[N:25][C:24]2[C:19](=[CH:20][C:21]([F:29])=[C:22]([F:28])[CH:23]=2)[N:18]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]참가 물질
4
반응 조건
- 온도
- 90 °C