Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
tert-Butyl (2S)-2-(aminomethyl)piperidine-1-carboxylate → (S)-2-([1,5]Naphthyridin-2-ylaminomethyl)-piperidine-1-carboxylic acid tert butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | tert-Butyl (2S)-2-(aminomethyl)piperidine-1-carboxylate | HCID 1502020 | — |
| 반응물 | 2-Chloro-1,5-naphthyridine | HCID 15153031 | — |
| 생성물 | (S)-2-([1,5]Naphthyridin-2-ylaminomethyl)-piperidine-1-carboxylic acid tert butyl ester | HCID 86593673 | — |
반응 단계
The title compound (0.48 g) was prepared from (S)-2-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester (0.59 g) and 2-chloro-1,5-naphthyridine Rapoport, et al J. Org. Chem. (1971), 36(3), 450-4 (0.40 g) according to the method of D30.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07741329B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-bce37ee91f1b41b695f60d5082862519 |
| 출처 메모 | uspto-grants-2010_06 |