tert-Butyl 2-(aminomethyl)piperidine-1-carboxylate → HCID 86593674, 화합물

HRID 18091노트

반응식

HRID 18091 반응식
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH:9]1[CH2:14][NH2:15])=[O:7])([CH3:4])([CH3:3])[CH3:2].CS[C:18]1[O:19][C:20]2[CH:26]=[CH:25][CH:24]=[N:23][C:21]=2[N:22]=1>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH:9]1[CH2:14][NH:15][C:18]1[O:19][C:20]2[CH:26]=[CH:25][CH:24]=[N:23][C:21]=2[N:22]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 2756482tert-Butyl 2-(aminomethyl)piperidine-1-carboxylateHCID 27640902-(Methylsulfanyl)-(1,3)oxazolo(4,5-b)pyridine

생성물 1

HCID 86593674HCID 86593674, 화합물

실험 절차

The title compound (0.7 g) was prepared from (RS)-2-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester (0.64 g) and 2-methylthio-4-azabenzoxazole Chu-Moyer et al J. Org. Chem. (1995), 60(17), 5721-5. (0.5 g) according to the method of D30.

출처 및 근거

ORD 기록
ord-b9980ce2038242daa2c978af4d852940
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07741329B2

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