Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric Acid → 3-Phenoxy-5-(trifluoromethyl)picolinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Ammonium Hydroxide | HCID 14923 | — |
| 반응물 | 3-Phenoxy-5-(trifluoromethyl)picolinonitrile | HCID 67485286 | — |
| 생성물 | 3-Phenoxy-5-(trifluoromethyl)picolinamide | HCID 67486645 | 84.3% |
반응 단계
3-Phenoxy-5-(trifluoromethyl)picolinonitrile (0.190 g, 0.719 mmol) was combined with 2 ml of sulfuric acid and agitated for 3 hours. Ice was added to the mixture, and the solution was basified with ammonium hydroxide solution. The resulting slurry was filtered and solids washed with water and dried in the air to afford 3-phenoxy-5-(trifluoromethyl)picolinamide (0.171 g, 84.3% yield) as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08362037B2 |
| 출처 데이터셋 | uspto-grants-2013_01 |
| ORD ID | ord-370172ece5634327b70de642dfe49b82 |
| 출처 메모 | uspto-grants-2013_01 |