3-Bromo-2-ethyl-1-benzofuran → HCID 178506734, 화합물

반응식

Br[C:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][C:3]=1[CH2:11][CH3:12].C([Li:17])CCC>>[Li:17][C:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][C:3]=1[CH2:11][CH3:12]

참가 물질

반응물 2

HCID 37907093-Bromo-2-ethyl-1-benzofuran

HCID 178418339Butyllithium

생성물 1

HCID 178506734HCID 178506734, 화합물

실험 절차

comprising contacting 3-bromo-2-ethylbenzofuran with n-butyllithium at a temperature less than −75° C. to form 3-lithio-2-ethylbenzofuran, contacting the 3-lithio-2-ethylbenzofuran at a temperature less than −75° C. with an isopropyl boronate cyclic ester corresponding to the formula:

후처리

customat a temperature less than −75° C.

출처 및 근거

ORD 기록: ord-cb5c7ed08f6845ca8044420d8e9ebdab
출처 데이터셋: uspto-grants-2013_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08362265B2

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