Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Nitro-2-oxindole → 5-Amino-2-oxindole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Nitro-2-oxindole | HCID 230366 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Dimethylacetamide | HCID 31374 | — |
| 생성물 | 5-Amino-2-oxindole | HCID 2773213 | 50.5% |
반응 단계
To a solution of 5-nitro-oxindole (25 g) in 120 mL of dimethylacetamide in a Parr bottle was added 10% Pd/C (0.5 g). The mixture was hydrogenated (40 psi H2) for 16 h. The catalyst was removed by filtration and the filtrate was diluted with ether (2 L) to provide 5-amino-oxindole (10.5 g; 50%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07741336B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-c74a7df036034b16a9d90a9fbaa46b63 |
| 출처 메모 | uspto-grants-2010_06 |