3-Chlorobenzenemethanethiol → 2-[[(3-Chlorophenyl)methyl]thio]-4-[[(1R)-2-hydroxy-1-methylethyl]amino]-7(8H)-pteridinone
반응식
F[C:2]1[C:7](F)=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:9][S:10]([C:13]1[N:22]=[C:21]([NH:23][C@H:24]([CH3:27])[CH2:25][OH:26])[C:20]2[N:19]=[CH:18][C:17](=[O:28])[NH:16][C:15]=2[N:14]=1)(=O)=O.[Cl:29]C1C=C(CS)C=CC=1>>[Cl:29][C:7]1[CH:2]=[C:3]([CH2:9][S:10][C:13]2[N:22]=[C:21]([NH:23][C@H:24]([CH3:27])[CH2:25][OH:26])[C:20]3[N:19]=[CH:18][C:17](=[O:28])[NH:16][C:15]=3[N:14]=2)[CH:4]=[CH:5][CH:6]=1참가 물질
3
실험 절차
The titled compound (66 mg) was prepared by the method of Example 13, step (c) using the product from Example 13, step (a) (0.20 g) and 3-chloro-benzenemethanethiol (92 mg).
출처 및 근거
- ORD 기록
- ord-a688e777ab89441982cd6b18492afb09
- 출처 데이터셋
- uspto-grants-2005_04