Dabsyl chloride → 1-(2-{1-[4-(4-Dimethylaminophenylazo)benzenesulfonyl]piperidin-4-yl}ethyl)-2-(ethoxymethyl)-6,7-dimethyl-1h-imidazo[4,5-c]pyridin-4-amine

HRID 1815028

반응식

HRID 1815028 반응식
[CH3:1][N:2]([C:4]1[CH:9]=[CH:8][C:7]([N:10]=[N:11][C:12]2[CH:17]=[CH:16][C:15]([S:18](Cl)(=[O:20])=[O:19])=[CH:14][CH:13]=2)=[CH:6][CH:5]=1)[CH3:3].[CH2:22]([O:24][CH2:25][C:26]1[N:27]([CH2:38][CH2:39][CH:40]2[CH2:45][CH2:44][NH:43][CH2:42][CH2:41]2)[C:28]2[C:33]([CH3:34])=[C:32]([CH3:35])[N:31]=[C:30]([NH2:36])[C:29]=2[N:37]=1)[CH3:23]>>[CH3:1][N:2]([CH3:3])[C:4]1[CH:9]=[CH:8][C:7]([N:10]=[N:11][C:12]2[CH:17]=[CH:16][C:15]([S:18]([N:43]3[CH2:44][CH2:45][CH:40]([CH2:39][CH2:38][N:27]4[C:28]5[C:33]([CH3:34])=[C:32]([CH3:35])[N:31]=[C:30]([NH2:36])[C:29]=5[N:37]=[C:26]4[CH2:25][O:24][CH2:22][CH3:23])[CH2:41][CH2:42]3)(=[O:20])=[O:19])=[CH:14][CH:13]=2)=[CH:6][CH:5]=1

참가 물질

3

반응물 2

HCID 91660Dabsyl chlorideHCID 129729622-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine

생성물 1

HCID 103123621-(2-{1-[4-(4-Dimethylaminophenylazo)benzenesulfonyl]piperidin-4-yl}ethyl)-2-(ethoxymethyl)-6,7-dimethyl-1h-imidazo[4,5-c]pyridin-4-amine

실험 절차

Using the method of Examples 49-56, 4-dimethylaminoazobenzene-4′-sulfonyl chloride was reacted with 2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired product. The observed accurate mass was 619.3185.

출처 및 근거

ORD 기록
ord-ff65ba1fff1a4832952168078b0adb09
출처 데이터셋
uspto-grants-2005_04
특허 번호
US06878719B2

연결된 노트

불러오는 중…