Ethyl Acetate → HCID 22493493, 화합물

HRID 1816227노트

반응식

HRID 1816227 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH:7][NH2:8].[CH3:9][S:10][C:11](SC)=[C:12]([C:16](=O)[CH3:17])[C:13](=[O:15])[CH3:14].C(OCC)(=O)C>[Cl-].[Na+].O>[CH3:17][C:16]1[N:7]([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)[N:8]=[C:11]([S:10][CH3:9])[C:12]=1[C:13](=[O:15])[CH3:14]

참가 물질

5

반응물 3

HCID 8857Ethyl AcetateHCID 786452-HydrazinopyridineHCID 27785933-[bis(methylsulfanyl)methylidene]pentane-2,4-dione

생성물 1

HCID 22493493HCID 22493493, 화합물

시약·촉매·용매 1

HCID 57417360Sodium chloride; water용매

반응 조건

온도
60 °C

실험 절차

A mixture of pyridin-2-yl-hydrazine (1.0 equivalent) and 3-(bis-methylsulfanyl-methylene)-pentane-2,4-dione (1.0 equivalent) was stirred at 60° C. overnight. To the reaction mixture was added ethyl acetate and brine, the organic phase was washed by brine twice, dried over magensium sulfate, and filtered. The organic solvent was removed under reduced pressure to provide the title compound.

후처리

  1. washthe organic phase was washed by brine twice
  2. dry with materialdried over magensium sulfate
  3. filtrationfiltered
  4. customThe organic solvent was removed under reduced pressure

출처 및 근거

ORD 기록
ord-8fce0c7a6c7e43f681bb815d7cb7e9a5
출처 데이터셋
uspto-grants-2005_04
특허 번호
US06884804B2

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