Isatoic Anhydride → HCID 22493286, 화합물

반응식

[NH2:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]([N:6]([CH:8]([CH3:10])[CH3:9])[CH3:7])=[O:5].[CH3:15][NH:16][CH:17]([CH3:19])C.C12C(=CC=CC=1)[NH:25][C:24](=O)OC2=O>>[NH:16]1[CH2:15][CH2:24][N:25]=[C:17]1[CH2:19][NH:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]([N:6]([CH:8]([CH3:10])[CH3:9])[CH3:7])=[O:5]

참가 물질

반응물 3

HCID 8359Isatoic Anhydride

HCID 78485N-Methylisopropylamine

HCID 167832852-amino-N-methyl-N-(propan-2-yl)benzamide

생성물 1

HCID 22493286HCID 22493286, 화합물

실험 절차

2-Amino-N-isopropyl-N-methylbenzamide (prepared from N-methylisopropylamine and isatoic anhydride, using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give 2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-N-isopropyl-N-methylbenzamide.