Isopropylamine → 2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-N-isopropylbenzamide

HRID 1816251

반응식

HRID 1816251 반응식
[NH2:1][C:2]1[CH:13]=[CH:12][CH:11]=[CH:10][C:3]=1[C:4]([NH:6][CH:7]([CH3:9])[CH3:8])=[O:5].[CH:14]([NH2:17])([CH3:16])C.[C:18]12[C:24](=CC=CC=1)[NH:23]C(=O)OC2=O>>[NH:17]1[CH2:14][CH2:16][N:23]=[C:24]1[CH2:18][NH:1][C:2]1[CH:13]=[CH:12][CH:11]=[CH:10][C:3]=1[C:4]([NH:6][CH:7]([CH3:9])[CH3:8])=[O:5]

참가 물질

4

반응물 3

HCID 6363IsopropylamineHCID 8359Isatoic AnhydrideHCID 944112-Amino-N-isopropylbenzamide

생성물 1

HCID 224933792-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-N-isopropylbenzamide

실험 절차

2-Amino-N-isopropylbenzamide (prepared from isopropylamine and isatoic anhydride, using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give 2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-N-isopropylbenzamide.

후처리

  1. customwere reacted

출처 및 근거

ORD 기록
ord-ee6c4ef5cbc744b1b35a72d37227c0bb
출처 데이터셋
uspto-grants-2005_04
특허 번호
US06884801B1

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