2-Amino-5-bromopyridine → N-(5-bromopyridin-2-yl)-N'-(2-fluoro-5-methylphenyl)urea

HRID 1817735

반응식

HRID 1817735 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=1.[F:9][C:10]1[CH:15]=[CH:14][C:13]([CH3:16])=[CH:12][C:11]=1[N:17]=[C:18]=[O:19].FC1C=CC=C(N=C=O)C=1>>[Br:8][C:5]1[CH:6]=[CH:7][C:2]([NH:1][C:18]([NH:17][C:11]2[CH:12]=[C:13]([CH3:16])[CH:14]=[CH:15][C:10]=2[F:9])=[O:19])=[N:3][CH:4]=1

참가 물질

4

반응물 3

HCID 706222-Amino-5-bromopyridineHCID 1230643-Fluorophenyl isocyanateHCID 27333772-Fluoro-5-methylphenyl isocyanate

생성물 1

HCID 66680783N-(5-bromopyridin-2-yl)-N'-(2-fluoro-5-methylphenyl)urea

실험 절차

The desired productwas prepared by substituting 2-amino5-bromopyridine and 1-fluoro-2-isocyanato-4-methylbenzene for Example 15G and 1-fluoro-3-isocyanatobenzene, respectively, in Example 15H. MS (ESI(+)) m/e 324.0 (M+H)+.

후처리

  1. customThe desired productwas prepared

출처 및 근거

ORD 기록
ord-51fa50946d914ed48ef4a604b8c8bf4d
출처 데이터셋
uspto-grants-2009_10
특허 번호
US07598283B2

연결된 노트

불러오는 중…