Benzyl Alcohol → 2-benzyloxy-7,7-dimethyl-7,8-dihydro-6H-quinolin-5-one hydrochloride

HRID 1817819노트

반응식

HRID 1817819 반응식
[Cl:1][C:2]1[CH:11]=[CH:10][C:9]2[C:8](=[O:12])[CH2:7][C:6]([CH3:14])([CH3:13])[CH2:5][C:4]=2[N:3]=1.[CH2:15]([OH:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[ClH:1].[CH2:15]([O:22][C:2]1[CH:11]=[CH:10][C:9]2[C:8](=[O:12])[CH2:7][C:6]([CH3:14])([CH3:13])[CH2:5][C:4]=2[N:3]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

참가 물질

3

반응물 2

HCID 244Benzyl AlcoholHCID 148125452-Chloro-7,7-dimethyl-7,8-dihydroquinolin-5(6H)-one

생성물 1

HCID 247775792-benzyloxy-7,7-dimethyl-7,8-dihydro-6H-quinolin-5-one hydrochloride수율 33%

실험 절차

In analogy to the procedure described in Example 9, 2-chloro-7,7-dimethyl-7,8-dihydro-6H-quinolin-5-one was treated with benzyl alcohol to give the title compound in 33% yield.

출처 및 근거

ORD 기록
ord-600370a55d4a4e10807f533d7bebb396
출처 데이터셋
uspto-grants-2009_10
특허 번호
US07598384B2

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