1-Fluoro-4-methanesulfonyl-2-nitrobenzene → HCID 61223503, 화합물

HRID 1817904노트

반응식

HRID 1817904 반응식
F[C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH3:11])(=[O:10])=[O:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].Cl.[NH2:16][CH2:17][C:18]1([OH:23])[CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH3:11][S:8]([C:5]1[CH:6]=[CH:7][C:2]([NH:16][CH2:17][C:18]2([OH:23])[CH2:22][CH2:21][CH2:20][CH2:19]2)=[C:3]([N+:12]([O-:14])=[O:13])[CH:4]=1)(=[O:10])=[O:9]

참가 물질

3

반응물 2

HCID 3131371-Fluoro-4-methanesulfonyl-2-nitrobenzeneHCID 211096931-(Aminomethyl)cyclopentan-1-ol--hydrogen chloride (1/1)

생성물 1

HCID 61223503HCID 61223503, 화합물

실험 절차

The title compound was prepared according to the procedure described in Step A of Example 5 from 1-fluoro-4-(methylsulfonyl)-2-nitrobenzene (Acros Organics) and 1-(aminomethyl)cyclopentanol hydrochloride (J. Med. Chem. 1981, 24, 7-12).

출처 및 근거

ORD 기록
ord-16957bf7536e43b7977332ebee12430f
출처 데이터셋
uspto-grants-2009_10
특허 번호
US07598393B2

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