1-Bromo-2-nitrobenzene → 7-Bromo-3-methyl-1H-indole

반응식

[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N+:8]([O-])=O.[CH2:11]([Mg]Br)[CH:12]=[CH2:13]>>[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]2[C:3]=1[NH:8][CH:11]=[C:12]2[CH3:13]

참가 물질

반응물 2

HCID 113411-Bromo-2-nitrobenzene

HCID 178455850HCID 178455850, 화합물

생성물 1

HCID 130306067-Bromo-3-methyl-1H-indole

실험 절차

2-Bromo nitrobenzene was reacted with allyl magnesium bromide according to the literature procedure (Dobbs A. J. Org Chem. 2001, 66, 638-641), to provide 7-bromo-3-methyl-1H-indole.

출처 및 근거

ORD 기록: ord-01b6c97a9cbc4daa9a7e8eccd097490d
출처 데이터셋: uspto-grants-2009_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07598397B2

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