1-(2-Chloroethyl)pyrrolidine → HCID 178454409, 화합물

HRID 1818408노트

반응식

HRID 1818408 반응식
[C:1]([N:6]1[CH2:11][CH2:10][CH:9]([N:12]([C@H:24]2[CH2:29][CH2:28][C@H:27]([CH3:30])[CH2:26][CH2:25]2)[C:13]([NH:15][C:16]2[S:17][C:18]([S:21]C#N)=[CH:19][N:20]=2)=[O:14])[CH2:8][CH2:7]1)(=[O:5])[CH2:2][CH2:3][CH3:4].SC[C@@H]([C@@H](CS)O)O.Cl[CH2:40][CH2:41][N:42]1[CH2:46][CH2:45][CH2:44][CH2:43]1>>[C:1]([N:6]1[CH2:11][CH2:10][CH:9]([N:12]([C@H:24]2[CH2:29][CH2:28][C@H:27]([CH3:30])[CH2:26][CH2:25]2)[C:13]([NH:15][C:16]2[S:17][C:18]([S:21][CH2:40][CH2:41][N:42]3[CH2:46][CH2:45][CH2:44][CH2:43]3)=[CH:19][N:20]=2)=[O:14])[CH2:8][CH2:7]1)(=[O:5])[CH2:2][CH2:3][CH3:4]

참가 물질

4

반응물 3

HCID 816691-(2-Chloroethyl)pyrrolidineHCID 439352DithioerythritolHCID 178454413HCID 178454413, 화합물

생성물 1

HCID 178454409HCID 178454409, 화합물

실험 절차

Prepared as described in general procedures (H) and (I) using 1-(1-butyryl-piperidin-4-yl)-1-(trans-4-methyl-cyclohexyl)-3-(5-thiocyanato-thiazol-2-yl)-urea, dithioerythritol and N-(2-chloroethyl)pyrrolidine.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-1d4f0c0d441a422e8124c8c56abce37b
출처 데이터셋
uspto-grants-2009_10
특허 번호
US07598391B2

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