1,4-Dioxane hydrochloride → 6-[(3R)-3-Aminopiperidin-1-yl]-5-(2-chlorobenzyl)-2-(3-ethoxyphenoxy)-3-methyl-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidine-7-carbonitrile hydrochloride

반응식

Cl.O1CCOCC1.[Cl:8][C:9]1[CH:52]=[CH:51][CH:50]=[CH:49][C:10]=1[CH2:11][N:12]1[C:20]2[C:19](=[O:21])[N:18]([CH3:22])[C:17]([O:23][C:24]3[CH:29]=[CH:28][CH:27]=[C:26]([O:30][CH2:31][CH3:32])[CH:25]=3)=[N:16][C:15]=2[C:14]([C:33]#[N:34])=[C:13]1[N:35]1[CH2:40][CH2:39][CH2:38][C@@H:37]([NH:41]C(=O)OC(C)(C)C)[CH2:36]1>O1CCOCC1>[ClH:8].[NH2:41][C@@H:37]1[CH2:38][CH2:39][CH2:40][N:35]([C:13]2[N:12]([CH2:11][C:10]3[CH:49]=[CH:50][CH:51]=[CH:52][C:9]=3[Cl:8])[C:20]3[C:19](=[O:21])[N:18]([CH3:22])[C:17]([O:23][C:24]4[CH:29]=[CH:28][CH:27]=[C:26]([O:30][CH2:31][CH3:32])[CH:25]=4)=[N:16][C:15]=3[C:14]=2[C:33]#[N:34])[CH2:36]1