Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(4-Chlorophenyl)-4-hydroxypiperidine → N-(1-(4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl)-4-(methylthio)-1-oxobutan-2-yl)benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(4-Chlorophenyl)-4-hydroxypiperidine | HCID 38282 | — |
| 반응물 | 3-Methyl-2-(phenylformamido)butanoic acid | HCID 226682 | — |
| 반응물 | Benzoyl-dl-methionine | HCID 295480 | — |
| 반응물 | 4-(4-chlorophenyl)piperidine Hydrochloride | HCID 2757843 | — |
| 생성물 | N-(1-(4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl)-4-(methylthio)-1-oxobutan-2-yl)benzamide | HCID 57889006 | — |
반응 단계
Example 217 was prepared in a similar manner as described for the preparation of Example 208 with the exceptions that benzoyl-DL-methionine and 4-(4-chlorophenyl)-4-hydroxypiperidine were substituted for benzoyl-DL-valine and 4-(4-chlorophenyl)piperidine hydrochloride, respectively. MS found: (M+H)+=448.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07601844B2 |
| 출처 데이터셋 | uspto-grants-2009_10 |
| ORD ID | ord-54dde8d92b244532a474e24aaaae48ed |
| 출처 메모 | uspto-grants-2009_10 |