1-Cyclooct-2-enylethanol → HCID 66957734, 화합물
반응식
[CH:1]1([CH:9]([OH:11])[CH3:10])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH:3]=[CH:2]1.[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>ClCCl>[CH:1]1([C:9](=[O:11])[CH3:10])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH:3]=[CH:2]1참가 물질
4
반응 조건
- 온도
- 20 °C
실험 절차
At 0° C., a solution of 1-cyclooct-2-enylethanol (1.4 g, 9 mmol) in dichloromethane (20 ml) was added to pyridiniumchlorochromate (2.35 g, 11 mmol) in dichloromethane (30 ml). The resulting mixture was stirred at 20° C. during 3.5 h and filtered through Celitee ®. The filtrate was concentrated and the crude product purified by flash chromatography (hexane/Et2O 6:1) to give 0.7 g of 1-cyclooct-2-enylethanone (55%).
후처리
- filtrationfiltered through Celitee ®
- concentrationThe filtrate was concentrated
- customthe crude product purified by flash chromatography (hexane/Et2O 6:1)
출처 및 근거
- ORD 기록
- ord-45df2b171d9a41b1881ddfc9dcdf5963
- 출처 데이터셋
- uspto-grants-2009_10
- 특허 번호
- US07605118B2
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