Sodium Methoxide → HCID 69038439, 화합물

HRID 1820759노트

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HRID 1820759 반응식
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[N:19]=[C:18](Cl)[N:17]=[CH:16][N:15]=2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH3:21][O-:22].[Na+]>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[N:19]=[C:18]([O:22][CH3:21])[N:17]=[CH:16][N:15]=2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 10942334Sodium MethoxideHCID 86600711845617-09-6

생성물 1

HCID 69038439HCID 69038439, 화합물

실험 절차

1 mmol of 4-(4-Chloro-[1,3,5]triazin-2-yl)-piperazine-1-carboxylic acid tert-butyl ester [example 4.11(a)] was dissolved in a solution of sodium methanolate (prepared by dissolving 1 mmol of sodium in 5 ml of methanol). The mixture was stirred at room temperature for 1 hour, concentrated and the title compound purified by recrystallisation from ethyl acetate/cyclohexane. MS (m/e): 296.3 (MH+, 100%)

후처리

  1. concentrationconcentrated
  2. customthe title compound purified by recrystallisation from ethyl acetate/cyclohexane

출처 및 근거

ORD 기록
ord-036b2c51955d4b00a5d8c7ebe73a6361
출처 데이터셋
uspto-grants-2009_10
특허 번호
US07605163B2

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