Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isopropanol → 5-Acetyl-2-isopropoxy-benzoic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isopropanol | HCID 3776 | — |
| 반응물 | Triphenylphosphine | HCID 11776 | — |
| 반응물 | Methyl 5-acetylsalicylate | HCID 85444 | — |
| 반응물 | Di-tert-butyl azodicarboxylate | HCID 97268 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 5-Acetyl-2-isopropoxy-benzoic acid methyl ester | HCID 69037473 | — |
반응 단계
To 25.8 mmol methyl-5-acetyl-2-hydroxybenzoate, 28.3 mmol 2-propanol and 29.6 mmol triphenylphosphine in 100 ml THF was added 28.3 mmol di-tert-butyl azodicarboxylate, and the mixture was stirred at RT for 90 min. The mixture was then concentrated in vacuo to afford the title compound. MS (m/e): 237.1 (M+H+, 100%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07605163B2 |
| 출처 데이터셋 | uspto-grants-2009_10 |
| ORD ID | ord-aa1c9460451844deab1594d3f6bbd099 |
| 출처 메모 | uspto-grants-2009_10 |