17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine → HCID 66933864, 화합물

HRID 1821454노트

반응식

HRID 1821454 반응식
NCCOCCOCC[O:10][CH2:11][CH2:12][NH:13][C:14]([CH2:16][CH2:17][C@H:18]([NH:26][C:27]([C:29]1[CH:34]=[CH:33][C:32]([N:35](C(OCC2C=CC=CC=2)=O)[CH3:36])=[CH:31][CH:30]=1)=[O:28])[C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])=[O:15].NCCO[CH2:51][CH2:52][O:53][CH2:54][CH2:55][O:56][CH2:57][CH2:58][O:59][CH2:60][CH2:61][O:62][CH2:63][CH2:64][N:65]=[N+]=[N-]>>[NH2:65][CH2:64][CH2:63][O:62][CH2:61][CH2:60][O:59][CH2:58][CH2:57][O:56][CH2:55][CH2:54][O:53][CH2:52][CH2:51][O:10][CH2:11][CH2:12][NH:13][C:14]([CH2:16][CH2:17][C@H:18]([NH:26][C:27]([C:29]1[CH:34]=[CH:33][C:32]([NH:35][CH3:36])=[CH:31][CH:30]=1)=[O:28])[C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])=[O:15]

참가 물질

3

반응물 2

HCID 2189447617-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amineHCID 66910315HCID 66910315, 화합물

생성물 1

HCID 66933864HCID 66933864, 화합물

실험 절차

Compound 26 (linker moity where n=5) was synthesized by an analogous procedure as employed for compound 12, but using 1-amino-17-azido-3,6,9,12,15-pentaoxaheptadecane instead of 1-amino-11-azido-3,6,9-trioxaundecane in the first step of synthesis.

후처리

  1. customin the first step of synthesis

출처 및 근거

ORD 기록
ord-41936ad1b5964491a6cc2a078e3891e6
출처 데이터셋
uspto-grants-2009_10
특허 번호
US07605175B2

반응 노트

불러오는 중…