Methylamine → HCID 10019152, 화합물

HRID 1823016노트

반응식

HRID 1823016 반응식
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([N:15]2[C:19](=[O:20])[CH2:18][CH:17]([C:21]([OH:23])=O)[CH2:16]2)=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:24][NH2:25]>>[CH3:24][NH:25][C:21]([CH:17]1[CH2:18][C:19](=[O:20])[N:15]([C:12]2[CH:13]=[CH:14][C:9]([O:8][CH2:1][C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)=[CH:10][CH:11]=2)[CH2:16]1)=[O:23]

참가 물질

3

반응물 2

HCID 6329MethylamineHCID 2968114STK087815

생성물 1

HCID 10019152HCID 10019152, 화합물수율 73%

실험 절차

The title compound is prepared in analogy to Example 20d) from (RS)-1-(4-benzyloxy-phenyl)-5-oxo-pyrrolidine-3-carboxylic acid and methylamine. Yield: 73% of a slightly yellow solid. MS: m/e=325.4 (M+H)+.

출처 및 근거

ORD 기록
ord-43038344913f4731a4541ea7038c6ee7
출처 데이터셋
uspto-grants-2006_05
특허 번호
US07037935B2

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