6-Chloro-2-dimethylamino-3-nitropyridine → {6-[(2-{[4-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-yl]amino}ethyl)amino]-3-nitro(2-pyridyl)}dimethylamine

HRID 1823497

반응식

HRID 1823497 반응식
ClC1C=C(Cl)C=CC=1C1C(C2NC=CN=2)=CN=C(CCN)N=1.Cl[C:24]1[N:29]=[C:28]([N:30]([CH3:32])[CH3:31])[C:27]([N+:33]([O-:35])=[O:34])=[CH:26][CH:25]=1.[Cl:36][C:37]1[CH:42]=[C:41]([Cl:43])[CH:40]=[CH:39][C:38]=1[C:44]1[C:49]([C:50]2[NH:51][CH:52]=[CH:53][N:54]=2)=[CH:48][N:47]=[C:46]([NH:55][CH2:56][CH2:57][NH:58]C2C=CC([N+]([O-])=O)=C(OC)N=2)[N:45]=1>>[Cl:36][C:37]1[CH:42]=[C:41]([Cl:43])[CH:40]=[CH:39][C:38]=1[C:44]1[C:49]([C:50]2[NH:54][CH:53]=[CH:52][N:51]=2)=[CH:48][N:47]=[C:46]([NH:55][CH2:56][CH2:57][NH:58][C:24]2[N:29]=[C:28]([N:30]([CH3:32])[CH3:31])[C:27]([N+:33]([O-:35])=[O:34])=[CH:26][CH:25]=2)[N:45]=1

참가 물질

4

반응물 3

HCID 217876256-Chloro-2-dimethylamino-3-nitropyridineHCID 22142635[4-(2,4-Dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(6-methoxy-5-nitro(2-pyridyl)) amino]ethyl}amineHCID 542317734-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-ylethylamine

생성물 1

HCID 22142601{6-[(2-{[4-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-yl]amino}ethyl)amino]-3-nitro(2-pyridyl)}dimethylamine

실험 절차

{6-[(2-{[4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]amino}ethyl)amino]-3-nitro(2-pyridyl)}dimethylamine was prepared from [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-ylethylamine and 6-chloro-2-dimethylamino-3-nitro pyridine in accordance with the procedure described above for the preparation of [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(6-methoxy-5-nitro(2-pyridyl))amino]ethyl}amine.

출처 및 근거

ORD 기록
ord-f0b4075f123c47b4a5df41786b27989f
출처 데이터셋
uspto-grants-2006_05
특허 번호
US07037918B2

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