4,6-Dichloropyrimidine → [4-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-yl]{2-[(6-chloropyrimidin-4-yl)amino]ethyl}amine

반응식

ClC1C=C(Cl)C=CC=1C1C(N2C=CN=C2)=CN=C(CCN)N=1.Cl[C:24]1[CH:29]=[C:28]([Cl:30])[N:27]=[CH:26][N:25]=1.[Cl:31][C:32]1[CH:37]=[C:36]([Cl:38])[CH:35]=[CH:34][C:33]=1[C:39]1[C:44]([C:45]2[NH:46][CH:47]=[CH:48][N:49]=2)=[CH:43][N:42]=[C:41]([NH:50][CH2:51][CH2:52][NH:53]C2C=CC([N+]([O-])=O)=C(OC)N=2)[N:40]=1>>[Cl:31][C:32]1[CH:37]=[C:36]([Cl:38])[CH:35]=[CH:34][C:33]=1[C:39]1[C:44]([C:45]2[NH:49][CH:48]=[CH:47][N:46]=2)=[CH:43][N:42]=[C:41]([NH:50][CH2:51][CH2:52][NH:53][C:24]2[CH:29]=[C:28]([Cl:30])[N:27]=[CH:26][N:25]=2)[N:40]=1

참가 물질

반응물 3

HCID 709434,6-Dichloropyrimidine

HCID 22142635[4-(2,4-Dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(6-methoxy-5-nitro(2-pyridyl)) amino]ethyl}amine

HCID 571748954-(2,4-Dichlorophenyl)-5-imidazol-1-ylpyrimidin-2-ylethylamine

생성물 1

HCID 22142648[4-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-yl]{2-[(6-chloropyrimidin-4-yl)amino]ethyl}amine

실험 절차

[4-(2,4-dichlorophenyl)-5-imidazolylpyrimidin-2-yl]{2-[(6-chloropyrimidin-4-yl)amino]ethyl}amine was prepared from [4-(2,4-dichlorophenyl)-5-imidazol-1-ylpyrimidin-2-ylethylamine and 4,6-dichloropyrimidine in accordance with the procedure described above for the preparation of [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(6-methoxy-5-nitro(2-pyridyl))amino]ethyl}amine.