HCID 178418800, 화합물 → 1-(2,4-Dichlorophenyl)-2-(4-methylimidazol-2-yl)ethan-1-one

반응식

[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9](=[O:16])[CH2:10][C:11]1C=CN[N:12]=1.[CH3:17][C:18]1[N:19]=CN[CH:22]=1>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9](=[O:16])[CH2:10][C:11]1[NH:12][CH:17]=[C:18]([CH3:22])[N:19]=1

참가 물질

반응물 2

HCID 178418800HCID 178418800, 화합물

HCID 178520323HCID 178520323, 화합물

생성물 1

HCID 1784308761-(2,4-Dichlorophenyl)-2-(4-methylimidazol-2-yl)ethan-1-one

실험 절차

Made using the same procedure as for 1-(2,4-dichlorophenyl)-2-pyrazolylethan-1-one except that 4-methylimidazole (3.7 g, 44.8 mmol) was used in place of pyrazole. The crude residue was purified on silica gel (5% MeOH/CH2Cl2) to yield a light yellow solid.

후처리

customThe crude residue was purified on silica gel (5% MeOH/CH2Cl2)
customto yield a light yellow solid

출처 및 근거

ORD 기록: ord-06f7342312d747f58e4a892ae58493e0
출처 데이터셋: uspto-grants-2006_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07037918B2

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