4-Fluorophenylboronic acid → 4-Methyl-5-(4-fluorophenyl)thiazole

HRID 1823973노트

반응식

HRID 1823973 반응식
[CH3:1][C:2]1[N:3]=[CH:4][S:5][C:6]=1Br.[F:8][C:9]1[CH:14]=[CH:13][C:12](B(O)O)=[CH:11][CH:10]=1>>[CH3:1][C:2]1[N:3]=[CH:4][S:5][C:6]=1[C:12]1[CH:13]=[CH:14][C:9]([F:8])=[CH:10][CH:11]=1

참가 물질

3

반응물 2

HCID 2856454-Fluorophenylboronic acidHCID 150209975-Bromo-4-methyl-1,3-thiazole

생성물 1

HCID 221479694-Methyl-5-(4-fluorophenyl)thiazole

실험 절차

Prepared from the bromothiazole from Step 1 and 4-fluorobenzeneboronic acid by the method described for Example 36 Step 3.

출처 및 근거

ORD 기록
ord-3a5f11b66e50447f8953a50605d18e54
출처 데이터셋
uspto-grants-2006_05
특허 번호
US07041689B2

반응 노트

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