Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,6-diethyl-N-(5-methoxy 1,2,3,4-tetrahydronaphthalen-1-yl)pyrazin-2-amine → 5-bromo-3,6-diethyl-N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)pyrazin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,6-diethyl-N-(5-methoxy 1,2,3,4-tetrahydronaphthalen-1-yl)pyrazin-2-amine | HCID 22147477 | — |
| 반응물 | (1R,2S)-1-[(5-bromo-3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol | HCID 58583245 | — |
| 생성물 | 5-bromo-3,6-diethyl-N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)pyrazin-2-amine | HCID 22147393 | — |
반응 단계
Following the procedure for the preparation of (1R,2S)-1-[(5-bromo-3,6-diethylpyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol but substituting 3,6-diethyl-N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)pyrazin-2-amine and making non-critical variations provided the title compound as a oil: 1H NMR (400 MHz, CDCl3) δ) 7.18, 6.97, 6.79, 5.37, 4.53, 2.87–2.76, 2.70–2.64, 2.54, 2.01–1.86, 1.35–1.24; HRMS (FAB) calcd for C19H24BrN3O+H 390.1181, found 390.1186.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07041672B2 |
| 출처 데이터셋 | uspto-grants-2006_05 |
| ORD ID | ord-26240153481e4401b0f1d22cc5c3d0aa |
| 출처 메모 | uspto-grants-2006_05 |