4,5,6,7-Tetrahydro-1-benzofuran-4-amine → 5-Ethyl-4,5,6,7-tetrahydro-1-benzothiophen-4-amine
반응식
O1[C:5]2[CH2:6][CH2:7][CH2:8][CH:9]([NH2:10])[C:4]=2[CH:3]=[CH:2]1.C(C1C(=O)C2[CH:18]=[CH:19][S:20]C=2CC1)C>>[CH2:3]([CH:4]1[CH:9]([NH2:10])[C:8]2[CH:18]=[CH:19][S:20][C:7]=2[CH2:6][CH2:5]1)[CH3:2]참가 물질
3
실험 절차
Following the procedure for the preparation of 4,5,6,7-tetrahydro-1-benzofuran-4-amine but substituting 5-ethyl-6,7-dihydro-1-benzothiophen-4(5H)-one and making non-critical variations provided the title compound as a oil: 1H NMR (400 MHz, CDCl3) δ) 7.10, 7.05, 6.99, 3.98, 3.65, 2.87–2.73, 2.06–1.90, 1.74–1.19, 1.05–0.97. (MS/CI) calcd for C10H15NS+H 182.3, found 181.9.
출처 및 근거
- ORD 기록
- ord-8e8777957b2846399c0c56e328406132
- 출처 데이터셋
- uspto-grants-2006_05
- 특허 번호
- US07041672B2
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