Piperidine → 4-Piperidinylbut-1-ene

HRID 1824547

반응식

HRID 1824547 반응식
Br[CH2:2][CH2:3][CH:4]=[CH2:5].[NH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1>>[N:6]1([CH2:7][CH2:8][CH:9]=[CH2:10])[CH2:11][CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

3

반응물 2

HCID 8082PiperidineHCID 21241Homoallyl bromide

생성물 1

HCID 45622824-Piperidinylbut-1-ene수율 93.4%

실험 절차

4-Bromobut-1-ene (1.35 g) was treated with piperidine (1.7 g) and heated at reflux for 3 hours. The mixture was cooled to ambient temperature, filtered and the residue washed with ether (50 mL). The combined filtrate and washings were evaporated to give the title compound (1.3 g).

후처리

  1. temperatureheated
  2. temperatureat reflux for 3 hours
  3. filtrationfiltered
  4. washthe residue washed with ether (50 mL)
  5. customThe combined filtrate and washings were evaporated

출처 및 근거

ORD 기록
ord-5c51527d0b6f4cf0b91aba41d78fbf5c
출처 데이터셋
uspto-grants-2006_05
특허 번호
US07041828B2

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