Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-[4-[4-Hydroxybut-1-ynyl]phenyl]-7-methylimidazo[1,2-a]pyridine → 2-[4-[4-Hydroxybutyl]phenyl]-7-methylimidazo[1,2-a]pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-[4-[4-Hydroxybut-1-ynyl]phenyl]-7-methylimidazo[1,2-a]pyridine | HCID 22015594 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-[4-[4-Hydroxybutyl]phenyl]-7-methylimidazo[1,2-a]pyridine | HCID 22015655 | 92.6% |
반응 단계
The product of Step B, Example 33 (0.3 g) in ethanol (15 mL) was hydrogenated over 5% palladium on barium sulfate (0.06 g) for 4.5 hours. The reaction mixture was filtered and evaporated to afford the title compound (0.282 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07041828B2 |
| 출처 데이터셋 | uspto-grants-2006_05 |
| ORD ID | ord-7dabd75f4f5445a89911f985c724bbc0 |
| 출처 메모 | uspto-grants-2006_05 |