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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1824554생성일: 2026년 10월 24일

2-[4-[(2,3-Epoxy)propoxy]phenyl]-8-methylimidazo[1,2-a]pyridine → 2-[4-(2-Hydroxy-3-propylaminopropoxy)phenyl]-8-methylimidazo[1,2-a]pyridine

https://huagongshe.com/ko/reaction/1824554

반응식

참여 물질

역할이름HCID투입량
반응물2-[4-[(2,3-Epoxy)propoxy]phenyl]-8-methylimidazo[1,2-a]pyridineHCID 22015632—
용매PropylamineHCID 7852—
생성물2-[4-(2-Hydroxy-3-propylaminopropoxy)phenyl]-8-methylimidazo[1,2-a]pyridineHCID 22015604—

반응 단계

The product of Step C (5.0 g) and propylamine (20 mL) was heated at 40° C. for 18 hours. The reaction was cooled to ambient temperature evaporated and the residue purified via silica gel chromatography (dichloromethane/methanol) to give the title compound which was converted to a HCl salt upon treatment with HCl/methanol.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07041828B2
출처 데이터셋uspto-grants-2006_05
ORD IDord-b89a0f4cb6f043ba843623570e4eed85
출처 메모uspto-grants-2006_05