Boron tribromide → HCID 22144519, 화합물

HRID 1824801노트

반응식

C[O:2][C:3]1[CH:20]=[CH:19][C:6]2[N:7]=[C:8]([C:10]3[CH:15]=[CH:14][CH:13]=[C:12]([O:16]C)[C:11]=3[Br:18])[S:9][C:5]=2[CH:4]=1.B(Br)(Br)Br>>[OH:2][C:3]1[CH:20]=[CH:19][C:6]2[N:7]=[C:8]([C:10]3[CH:15]=[CH:14][CH:13]=[C:12]([OH:16])[C:11]=3[Br:18])[S:9][C:5]=2[CH:4]=1

참가 물질

반응물 2

HCID 25134Boron tribromide

HCID 22144554HCID 22144554, 화합물

생성물 1

HCID 22144519HCID 22144519, 화합물수율 26.4%

실험 절차

6-Methoxy-2-(2-bromo-3-methoxy-phenyl)-benzothiazole (0.144 g, 0.411 mmol) was treated with boron tribromide under standard condition to give 6-hydroxy-2-(2-bromo-3-hydroxy-phenyl)-benzothiazole (35 mg, 26% yield) as a yellow solid. Mass spec: MH+=322.

출처 및 근거

ORD 기록: ord-823265e2d63845a699833c739f9ca990
출처 데이터셋: uspto-grants-2006_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07045539B2

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