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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1825197생성일: 2026년 10월 27일

2-(6-fluoro-1H-indol-3-yl)ethanamine → 2-Methyl-6-(thieno[3,2-b]pyridin-7-yloxy)-benzofuran-3-carboxylic acid [2-(6-fluoro-1H-indol-3-yl)-ethyl]-amide

https://huagongshe.com/reaction/1825197

반응식

참여 물질

역할이름HCID투입량
반응물2-(6-fluoro-1H-indol-3-yl)ethanamineHCID 854024—
반응물2-Methyl-6-[thieno[3,2-b]pyridin-7-yloxy]benzofuran-3-carboxylic acidHCID 22143510—
생성물2-Methyl-6-(thieno[3,2-b]pyridin-7-yloxy)-benzofuran-3-carboxylic acid [2-(6-fluoro-1H-indol-3-yl)-ethyl]-amideHCID 20767889—

반응 단계

This material was prepared from 2-methyl-6-[thieno[3,2-b]pyridin-7-yloxy]benzofuran-3-carboxylic acid 100 and 2-(6-fluoro-1H-indol-3-yl)ethylamine in a similar manner as that described for example 102. 1H NMR (CD3CN) δ 8.48 (1H, d, J=5.6 Hz), 7.91 (1H, d, J=5.6 Hz), 7.63–7.59 (2H, m), 7.54 (1H, d, J=5.6 Hz), 7.38 (1H, d, J=2.3 Hz), 7.17 (1H, d, J=2.3 Hz), 7.14 (1H, t, J=2.3 Hz), 7.11 (1H, d, J=2.3 Hz), 6.85 (1H, m), 6.65 (1H, bm), 6.61 (1H, d, J=5.6 Hz), 3.69 (2H, q, J=7.1 Hz), 3.06 (2H, t, J=7.1 Hz), 2.57 (3H, s).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07045528B2
출처 데이터셋uspto-grants-2006_05
ORD IDord-1209fcaa5f994665a4b0f8f116c19a6c
출처 메모uspto-grants-2006_05