Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 5-Bromo-6-methoxy-2-methylthioquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 5-Bromo-2-methanesulfonyl-6-methoxy-quinoline | HCID 22139732 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 5-Bromo-6-methoxy-2-methylthioquinoline | HCID 22139696 | — |
반응 단계
The 5-bromo-2-methanesulfonyl-6-methoxy-quinoline was dissolved in 20 mL DMF and treated with 3 eq NaSCH3. After stirring 1 hour at room temperature the mixture was poured into water and extracted with ether. The crystalline product, 5-bromo-6-methoxy-2-methylsulfanyl-quinoline, was isolated in quantitative yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07049325B2 |
| 출처 데이터셋 | uspto-grants-2006_05 |
| ORD ID | ord-0b7c09262ddf44c49e91fbe659baecaf |
| 출처 메모 | uspto-grants-2006_05 |