Ethyl indole-2-carboxylate → 7-Fluoro-1-methylindole-3-carboxaldehyde

HRID 18260

반응식

HRID 18260 반응식
[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][CH:8]=[C:7]2[CH:11]=[O:12].N1C2C(=CC=CC=2)C=[C:14]1C(OCC)=O>>[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH3:14])[CH:8]=[C:7]2[CH:11]=[O:12]

참가 물질

3

실험 절차

According to the procedure of Preparation 9 (a), except substituting 7-fluoro-1H-indole-3-carboxaldehyde (0.5 g, 3.1 mmole) for the ethyl indole-2-carboxylate, the title compound (0.23 g, 43%) was prepared as a viscous oil: MS (ES) m/e 178 (M+H)+.

출처 및 근거

ORD 기록
ord-ff2ee5770f174403ba474c3949bbf8f4
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07741339B2

연결된 노트

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