Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-dimethyl-1H-indole-2-carbaldehyde → 6-fluoro-1-methyl-3-(methylaminomethyl)-1H-indole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-dimethyl-1H-indole-2-carbaldehyde | HCID 2771468 | — |
| 반응물 | 6-Fluoro-1-methyl-1H-indole-3-carbaldehyde | HCID 6498197 | — |
| 반응물 | Methyl 2-((5-bromopyridin-2-yl)amino)acetate | HCID 22139049 | — |
| 생성물 | 6-fluoro-1-methyl-3-(methylaminomethyl)-1H-indole | HCID 22139158 | 35% |
반응 단계
According to the procedure of Preparation 11 (c), except substituting 6-fluoro-1-methyl-1H-indole-3-carboxaldehyde (0.3 g, 1.69 mmole) for the 1,3-dimethyl-1H-indole-2-carboxaldehyde, the title compound (0.11 g, 35%) was prepared as a viscous oil: MS (ES) m/e 193 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07741339B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-00e4e9be91044d3da0f4b338f7404e08 |
| 출처 메모 | uspto-grants-2010_06 |