Diethyl Ether → HCID 178481604, 화합물

HRID 1826517노트

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HRID 1826517 반응식
[CH3:1][N:2]1[C:7](=[O:8])[CH:6]=[C:5]([C:9]2[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=2)[N:4]=[C:3]1SC.[N+:17]([O-])([O-:19])=[O:18].[K+].C([O:24]CC)C>S(=O)(=O)(O)O>[OH:24][C:3]1[N:2]([CH3:1])[C:7](=[O:8])[C:6]([N+:17]([O-:19])=[O:18])=[C:5]([C:9]2[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=2)[N:4]=1

참가 물질

5

반응물 3

HCID 3283Diethyl EtherHCID 24434Potassium NitrateHCID 155215183-methyl-2-methylsulfanyl-6-pyridin-4-yl-3H-pyrimidin-4-one

생성물 1

HCID 178481604HCID 178481604, 화합물

시약·촉매·용매 1

HCID 1118Sulfuric Acid용매

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온도
70 °C

실험 절차

To a stirring solution of 3-methyl-2-methylsulfanyl-6-pyridin-4-yl-3H-pyrimidin-4-one (15.5 mmol) in 40 mL sulfuric acid was added potassium nitrate (62.1 mmol). The reaction was heated to 70° C. for 3 h. Reaction was then added to stirring diethyl ether (400 mL), and precipitate collected by filtration. The precipitate was suspended in water and the pH was adjusted to 3 using sodium hydroxide. The solid was collected by filtration. M+1=249.

후처리

  1. customReaction
  2. additionwas then added
  3. filtrationcollected by filtration
  4. filtrationThe solid was collected by filtration

출처 및 근거

ORD 기록
ord-0d9e616a7c984ad496bfa4dee869fc4e
출처 데이터셋
uspto-grants-2006_05
특허 번호
US07049318B2

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