Nitronium tetrafluoroborate → HCID 22139632, 화합물

HRID 1826523노트

반응식

HRID 1826523 반응식
[CH3:1][N:2]1[C:7](=[O:8])[CH:6]=[C:5]([C:9]2[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=2)[N:4]=[C:3]1[CH:15]1[CH2:20][CH2:19][N:18]([CH3:21])[CH2:17][CH2:16]1.F[B-](F)(F)F.[O:27]=[N+:28]=[O:29]>C(#N)C>[CH3:1][N:2]1[C:7](=[O:8])[C:6]([N+:28]([O-:29])=[O:27])=[C:5]([C:9]2[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=2)[N:4]=[C:3]1[CH:15]1[CH2:20][CH2:19][N:18]([CH3:21])[CH2:17][CH2:16]1

참가 물질

4

반응물 2

HCID 11073463Nitronium tetrafluoroborateHCID 221395743-Methyl-2-(1-methylpiperidin-4-yl)-6-(pyridin-4-yl)pyrimidin-4(3H)-one

생성물 1

HCID 22139632HCID 22139632, 화합물

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

To a solution of 3-methyl-2-(1-methyl-piperidin-4-yl)-6-pyridin-4-yl-3H-pyrimidin-4-one (0.64 mmol) in acetonitrile (2.5 mL) at 0° C. was added 2.5 mL 0.5M solution of nitronium tetrafluoroborate. After 30 min, the reaction product was isolated and purified on silica. M+1=329.

후처리

  1. customthe reaction product was isolated
  2. custompurified on silica

출처 및 근거

ORD 기록
ord-513e238e47a841b2b43efcb8f9e71de2
출처 데이터셋
uspto-grants-2006_05
특허 번호
US07049318B2

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