Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dicyclohexylcarbodiimide → 4-(5-Undecyl-pyrimidin-2-yl)phenyl 3-ethyl-1-cyclopentene-1-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dicyclohexylcarbodiimide | HCID 10868 | — |
| 반응물 | 3-Ethyl-1-cyclopentene-1-carboxylic acid | HCID 22134221 | — |
| 반응물 | 4-(5-Undecylpyrimidin-2-yl)phenol | HCID 135619682 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-(5-Undecyl-pyrimidin-2-yl)phenyl 3-ethyl-1-cyclopentene-1-carboxylate | HCID 15514978 | — |
반응 단계
4.9 g of 4-(5-undecyl-pyrimidin-2-yl)phenol, 1.5 g of 3-ethyl-1-cyclopentene-1-carboxylic acid and 2.1 g of dicyclohexylcarbodiimide are stirred for 24 h in 50 ml of dichloromethane at room temperature. Filtration, removal of the dichloromethane by distillation, purification by chromatography (silica gel; dichloromethane/heptane) and recrystallization from acetonitrile affords the target compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07052742B1 |
| 출처 데이터셋 | uspto-grants-2006_05 |
| ORD ID | ord-4322494066cc4a929d8fbfd18ddf3161 |
| 출처 메모 | uspto-grants-2006_05 |