(R)-2-(4-Methoxybenzoylamino)-2-phenylethylazide → (R)-2-(4-methoxybenzoylamino)-2-phenylethylamine

HRID 1826600노트

반응식

HRID 1826600 반응식
[CH3:1][O:2][C:3]1[CH:22]=[CH:21][C:6]([C:7]([NH:9][C@H:10]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:11][N:12]=[N+]=[N-])=[O:8])=[CH:5][CH:4]=1>C1COCC1>[CH3:1][O:2][C:3]1[CH:22]=[CH:21][C:6]([C:7]([NH:9][C@H:10]([C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)[CH2:11][NH2:12])=[O:8])=[CH:5][CH:4]=1

참가 물질

3

반응물 1

HCID 53998160(R)-2-(4-Methoxybenzoylamino)-2-phenylethylazide

생성물 1

HCID 54421380(R)-2-(4-methoxybenzoylamino)-2-phenylethylamine

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

Using Deprotection Method A, (R)-2-(4-methoxybenzoylamino)-2-phenylethyl azide (46.3 g) in THF (400 mL) afforded, after recrystallization with ethyl acetate, 35.4 g (84%) of the title compound.

후처리

  1. customafforded
  2. customafter recrystallization with ethyl acetate, 35.4 g (84%) of the title compound

출처 및 근거

ORD 기록
ord-beb753aedf0a4158be152aa4f5a70f3e
출처 데이터셋
uspto-grants-2006_05
특허 번호
US07053078B2

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