4-(Piperidin-4-yl)indolin-2-one → HCID 24941216, 화합물

HRID 1826764노트

반응식

HRID 1826764 반응식
[NH:1]1[CH2:6][CH2:5][CH:4]([C:7]2[CH:15]=[CH:14][CH:13]=[C:12]3[C:8]=2[CH2:9][C:10](=[O:16])[NH:11]3)[CH2:3][CH2:2]1.[CH2:17]([O:19][C:20]([C:22]1[C:26]([CH2:27][CH2:28][C:29]([OH:31])=[O:30])=[C:25]([CH:32]=O)[NH:24][C:23]=1[CH3:34])=[O:21])[CH3:18]>>[CH2:17]([O:19][C:20]([C:22]1[C:26]([CH2:27][CH2:28][C:29]([OH:31])=[O:30])=[C:25]([CH:32]=[C:9]2[C:8]3[C:12](=[CH:13][CH:14]=[CH:15][C:7]=3[CH:4]3[CH2:3][CH2:2][NH:1][CH2:6][CH2:5]3)[NH:11][C:10]2=[O:16])[NH:24][C:23]=1[CH3:34])=[O:21])[CH3:18]

참가 물질

3

반응물 2

HCID 221353964-(Piperidin-4-yl)indolin-2-oneHCID 545693914-(2-carboxyethyl)-5-formyl-2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester

생성물 1

HCID 24941216HCID 24941216, 화합물

실험 절차

4-Piperidin-4-yl-1,3-dihydroindol-2-one (45 mg, 0.2 mmol) was condensed with 4-(2-carboxyethyl)-5-formyl-2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester (56 mg, 0.23 mmol) to give the title compound.

출처 및 근거

ORD 기록
ord-7bc61bbae85d4e858c6a6428419b4c09
출처 데이터셋
uspto-grants-2006_05
특허 번호
US07053086B2

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