HCID 202244, 화합물 → HCID 13135811, 화합물
반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][C:10]2[CH:15]=[CH:14][C:13]([NH2:16])=[CH:12][CH:11]=2)=[CH:4][CH:3]=1>O1CCCC1.[Pd]>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][CH2:9][C:10]2[CH:11]=[CH:12][C:13]([NH2:16])=[CH:14][CH:15]=2)=[CH:6][CH:7]=1참가 물질
4
실험 절차
3.46 g of 4-[2-(4-fluoro-phenyl)-vinyl]-phenylamine is dissolved in 100 ml of tetrahydrofuran, treated with 350 mg of palladium 10% on charcoal and hydrogenated at room temperature and normal pressure for about 4 h. The catalyst is filtered off and the filtrate concentrated to yield 3.46 g (99%) of a yellow solid. MS: m/e=216.9 (M++H).
후처리
- filtrationThe catalyst is filtered off
- concentrationthe filtrate concentrated
출처 및 근거
- ORD 기록
- ord-dc563ef7b2934bf993366703aedebf4f
- 출처 데이터셋
- uspto-grants-2006_05
- 특허 번호
- US07053245B2
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