Piperidin-4-ol → 8-(1-(3-chloro-2-fluorophenylamino)ethyl)-6-(4-hydroxypiperidine-1-carbonyl)-2-morpholino-4H-chromen-4-one

반응식

[Cl:1][c:2]1[c:3]([F:31])[c:4]([NH:8][CH:9]([CH3:10])[c:11]2[cH:12][c:13]([C:28](=[O:29])[OH:30])[cH:14][c:15]3[c:16](=[O:27])[cH:17][c:18]([N:21]4[CH2:22][CH2:23][O:24][CH2:25][CH2:26]4)[o:19][c:20]23)[cH:5][cH:6][cH:7]1.[NH:32]1[CH2:33][CH2:34][CH:35]([OH:38])[CH2:36][CH2:37]1>>[Cl:1][c:2]1[c:3]([F:31])[c:4]([NH:8][CH:9]([CH3:10])[c:11]2[cH:12][c:13]([C:28](=[O:29])[N:32]3[CH2:33][CH2:34][CH:35]([OH:38])[CH2:36][CH2:37]3)[cH:14][c:15]3[c:16](=[O:27])[cH:17][c:18]([N:21]4[CH2:22][CH2:23][O:24][CH2:25][CH2:26]4)[o:19][c:20]23)[cH:5][cH:6][cH:7]1

참가 물질

반응물 2

HCID 79341Piperidin-4-ol

HCID 582350028-(1-(3-chloro-2-fluorophenylamino) ethyl)-2-morpholino-4-oxo-4H-chromene-6-carboxylic acid

생성물 1

HCID 529135918-(1-(3-chloro-2-fluorophenylamino)ethyl)-6-(4-hydroxypiperidine-1-carbonyl)-2-morpholino-4H-chromen-4-one

출처 및 근거

ORD 기록: ord-1f791835190640f4b15014c97ba02f3a
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…