Skatole → 4-Chloro-1-methyl-1H-indole

반응식

[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][NH:6]2.[CH3:11]C1C2C(=CC=CC=2)NC=1>>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][N:6]2[CH3:11]

참가 물질

반응물 2

HCID 6736Skatole

HCID 913454-Chloroindole

생성물 1

HCID 130487594-Chloro-1-methyl-1H-indole수율 100%

실험 절차

According to the procedure of Preparation 13 (a), except substituting 4-chloroindole for the 3-methylindole, the title compound (2.2 g, 100%) was obtained as an amber oil: MS (ES) m/e 166.0 (M+H)+.

출처 및 근거

ORD 기록: ord-9ecece90d71f49e38ad0702522d1c7ad
출처 데이터셋: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07741339B2

반응 노트

불러오는 중…