3-Methoxy-4-methyl-2-nitropyridine → 2-Pyridinamine,3-methoxy-4-methyl-(9CI)

HRID 1828529노트

반응식

HRID 1828529 반응식
[CH3:1][O:2][C:3]1[C:4]([N+:10]([O-])=O)=[N:5][CH:6]=[CH:7][C:8]=1[CH3:9]>CO.[Pd]>[NH2:10][C:4]1[C:3]([O:2][CH3:1])=[C:8]([CH3:9])[CH:7]=[CH:6][N:5]=1

참가 물질

4

반응물 1

HCID 149295773-Methoxy-4-methyl-2-nitropyridine2회

생성물 1

HCID 220637652-Pyridinamine,3-methoxy-4-methyl-(9CI)수율 103.4%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

The 3-methoxy-4-methyl-2-nitropyridine (1 g) obtained in (A) was dissolved in methanol (50 ml), added with 5% Pd/C (200 mg), and stirred at a pressure of 40 psi for 2 hours under hydrogen atmosphere. After the catalyst was removed by filtration, the solvent was evaporated under reduced pressure to obtain the title compound (850 mg) as yellow oil.

후처리

  1. customAfter the catalyst was removed by filtration
  2. customthe solvent was evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-51b8d38c280b4a1b873c80a8120d7d35
출처 데이터셋
uspto-grants-2006_06
특허 번호
US07056917B2

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