Diethylamine → HCID 22059719, 화합물

HRID 1828899노트

반응식

HRID 1828899 반응식
[CH2:1]([NH:3][CH2:4][CH3:5])[CH3:2].Cl[CH2:7][C:8]([C:10]1[C:11]([CH3:18])=[C:12]([CH:16]=[O:17])[NH:13][C:14]=1[CH3:15])=[O:9]>C1COCC1>[CH3:18][C:11]1[C:10]([C:8](=[O:9])[CH2:7][N:3]([CH2:4][CH3:5])[CH2:1][CH3:2])=[C:14]([CH3:15])[NH:13][C:12]=1[CH:16]=[O:17]

참가 물질

4

반응물 2

HCID 8021DiethylamineHCID 220598554-(2-chloroacetyl)-3,5-dimethyl-1H-pyrrole-2-carbaldehyde

생성물 1

HCID 22059719HCID 22059719, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

Diethylamine (5 ml) was added to a solution of 4-(2-Chloroacetyl)-3,5-dimethylpyrrole-2-carboxaldehyde (1 g, 5 mmol) in THF (20 ml). The mixture was stirred at room temperature for 24 h. The solvent was removed under reduced pressure and the residue was treated with water, NaHCO3 (5%) and extracted with dichloromethane. After drying and filtering, the solvent was removed and the residue was used without further purification.

후처리

  1. customThe solvent was removed under reduced pressure
  2. additionthe residue was treated with water, NaHCO3 (5%)
  3. extractionextracted with dichloromethane
  4. customAfter drying
  5. filtrationfiltering
  6. customthe solvent was removed
  7. customthe residue was used without further purification

출처 및 근거

ORD 기록
ord-f5763b2445974eb093d9337134f23510
출처 데이터셋
uspto-grants-2006_06
특허 번호
US07060822B1

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