Ethyl indole-2-carboxylate → methyl 1-methyl-1H-indole-7-carboxylate

HRID 18300

반응식

HRID 18300 반응식
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2[C:10]([O:12][CH3:13])=[O:11])[CH:3]=[CH:2]1.N1C2C(=CC=CC=2)C=[C:15]1C(OCC)=O>>[CH3:15][N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][C:8]=2[C:10]([O:12][CH3:13])=[O:11])[CH:3]=[CH:2]1

참가 물질

3

반응물 2

HCID 73125Ethyl indole-2-carboxylateHCID 676694Methyl indole-7-carboxylate

생성물 1

HCID 10821478methyl 1-methyl-1H-indole-7-carboxylate수율 90%

실험 절차

According to the procedure of Preparation 9 (a), except substituting methyl indole-7-carboxylate for the ethyl indole-2-carboxylate, the title compound (2.4 g, 90%) was obtained as an oil: MS (ES) m/e 190.2 (M+H)+.

출처 및 근거

ORD 기록
ord-ec600b9a03df41abab030bf8e0e763b6
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07741339B2

연결된 노트

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