Thionicotinamide → HCID 22049723, 화합물

반응식

Br[CH2:2][C:3]([C:5]1[CH:6]=[N:7][CH:8]=[CH:9][C:10]=1[CH3:11])=O.[C:12]([NH2:20])(=[S:19])[C:13]1[CH:18]=[CH:17][CH:16]=[N:15][CH:14]=1>>[CH3:11][C:10]1[CH:9]=[CH:8][N:7]=[CH:6][C:5]=1[C:3]1[N:20]=[C:12]([C:13]2[CH:14]=[N:15][CH:16]=[CH:17][CH:18]=2)[S:19][CH:2]=1

참가 물질

반응물 2

HCID 737155Thionicotinamide

HCID 220497832-Bromo-1-(4-methylpyridin-3-yl)ethan-1-one

생성물 1

HCID 22049723HCID 22049723, 화합물수율 39.5%

실험 절차

By the reaction in the same manner as in Example 25-iii) using 2-bromo-1-(4-methylpyridin-3-yl)ethanone hydrobromate (432 mg) and thionicotinamide (152 mg), the title compound (110 mg) was obtained as colorless powder crystals.

후처리

customBy the reaction in the same manner as in Example 25-iii)

출처 및 근거

ORD 기록: ord-8d9b41d4397d4d188d3dd4e000bc0f14
출처 데이터셋: uspto-grants-2006_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07067537B2

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